The endocannabinoid system

What is the endocannabinoid system and how does it work?
A summary of various known and unknown sources from the Internet.

One of the latest and most striking scientific discoveries. ECS regulates a variety of biological processes such as relaxation, nutrition, sleep, certain inflammatory reactions and even cognitive functions. In short, your ECS is responsible for the optimal function of your body. This is not an easy task!

Endocannabinoids and their receptors are found throughout the body. However, while the endocannabinoid system performs its functions, the ECS acts as a regulator of homeostasis, according to experts. Such a complex system as the ECS is difficult to define. However, it is important to know that there are two important receptors in the body cells: CB1 and CB2. They are abundant in the brain and immune system. The body produces cannabinoids in a natural process (e.g. endocannabinoids: anandamides and 2-AG), which have similar chemical structures to cannabinoids of plant origin as CBD.

 

 

 

 

 

 

Scientists first discovered the endocannabinoid system when they tried to understand the effects of cannabis on humans. While much is still unknown about this system, we know that our body has many cannabinoid receptors and produces molecules that are responsible for the physical and psychological effects of cannabis in our body. Have you ever wondered why cannabis can act so effectively on your body? Well, it’s this system!

Since its discovery, the endocannabinoid system has become a priority object of medical research because of its enormous effects and therapeutic potential for the human body.

Endocannabinoids (and plant cannabinoids) combine with receptors called cannabinoid receptors on the cell surface. There are two main receptors, CB1 and CB2, and cannabidiol (CBD) has been shown to strengthen and increase the efficiency of mitochondria, which are the driving force for every cell in your body. Studies on the endocannabinoid system (ECS) have shown that in addition to its role as a regulator of homeostasis, ECS is also responsible for the repair of damaged cells. The investigations also show that cannabinoids are able to specifically recognise damaged cells without influencing healthy cells. This means that the ECS can act as a biological defence system. When a person ingests hemp oil, CBD or other cannabinoids, these cannabinoid receptors are activated (the CBD seems to have a higher affinity for CB2 receptors than for CB1 receptors). Research suggests that supplementing your ECS with non-toxic and non-addictive cannabinoids will make it possible to develop a healthier endocannabinoid system and almost certainly a healthier lifestyle.

The two major endocannabinoids that are well understood today are:

Anandamide: The first endocannabinoid discovered by scientists. His name comes from the Sanskrit word “Ananda”, which means “bliss”. It is found in higher concentrations in body regions remote from the brain.

2-AG (2-eachidonoylglycerin): Highest concentrations occur in the brain.

These endocannabinoids are called “short-term” neurotransmitters because they are only synthesized when the body signals that it needs them acutely. After their release, they are rapidly degraded by enzymes such as FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). There are many other endocannabinoids such as noladine ether, virodhamin and N-arachidonoyldopamine (NADA). However, their role in the body has not yet been fully decoded.

The body produces endocannabinoids to trigger essential physical functions and patterns. Ethan Russo, a senior consultant at GW Pharmaceuticals, believes that “deficient cannabinoid levels can be the underlying cause of many diseases. This deficiency could possibly cause severe diseases such as chronic pain or fibromyalgia associated with the endocannabinoid system.

CBD

CBD does not actually bind to any receptors, but instead acts as an inhibitor of the enzyme FAAH, which slows down or prevents the degradation of anandamide – possibly one of the most important endocannabinoids in the body. The result is a build-up of anandamide in the brain.

While we are aware that THC has an obvious psychological effect on the mind, CBD is considered effective on the physiological level, although we have only just begun to discover its medical benefits. However, it is well known that CBD helps in the treatment of serious medical conditions, including inhibition of tumor growth, reduction or prevention of inflammation and nausea, diabetes, PTSD, schizophrenia, rheumatoid arthritis, epilepsy, cardiovascular disease, psychosis, anxiety disorders and even as a pain reliever for muscle spasms or neuropathic pain.

Researchers are studying cannabinoids and other compounds to see how they interact with the endocannabinoid system.
CBD and THC are not the only compounds used by the endocannabinoid system. There are at least eighty phyto-cannabinoids, different endocannabinoids. These are the cannabinoids that all mammals produce in their bodies, as well as some other compounds, such as omega fatty acids, that interact with cannabinoid receptors.

Thousands of studies have been published and reviewed on the subject of the endocannabinoid system. Since its discovery more than two decades ago, the endocannabinoid system has aroused interest in pharmaceutical drug development and research. In general, this research shows that the endocannabinoid system seems to play a strongly “protective” role in our body. In fact, the most important thing the endocannabinoid system wants to protect is homeostasis – that is, ensuring that the body functions optimally at all times. Some researchers have suggested an “endocannabinoides syndrome”, a syndrome in which the body does not produce enough endocannabinoids. This research speculates that a lack of cannabinoids may be related to autoimmune diseases such as lupus, rheumatoid arthritis, diabetes and many more.
As a company, Kannaway is absolutely committed to research into the endocannabinoid system. If research continues in the current direction, it can be argued that the endocannabinoid system is a key system for the general well-being of humans!

You can find high-quality products in my shop (forwarding):

The shop of Juttakann

Before or after an order you are welcome to contact us, as we occasionally give away vouchers.

Kannaway’s Pure Gold is for me (after many tests of different CBD oils) the most effective CBD hemp oil product available on the Eropean market for some time!

Jutta Ferchow

Stefan Lueke

Sources:

Wikipedia

Kannaway

Freely reproduced translations of various articles

A short thought about network marketing / recommendation marketing

Many people associate network marketing with the idea that many people earn money and that the products actually have to cost much less. At the same time, however, prices in retail and online trade are usually more or less accepted. Some people also like to buy products with which “fair” trade etc. stands.

Rarely one or more thoughts are wasted then actually once on it like the costs in the retail trade look and which the producer actually receives. If you can see the show “Dragons’ Den” from time to time, you might want to think about this cost – selling price situation, because as soon as a candidate says that his product costs 20% of the final selling price, the interest of these “dragons” disappears suddenly.

I can only list one product here as an example where I was completely involved from production to sale.

I now bridle the horse from behind.

1 kg paprika costs up to 5.99 euros at REWE.

But I’ll only take 4.99 euros now.

REWE sometimes buys this from the middleman in Europe for 1 euro, on average 1.50 euro.

Of course REWE has to pay for advertising, buildings, employees, etc. and above all shareholders.

The middleman (who of course has costs and wants to make a profit) buys the kilo from the local middleman (in this case Morocco) for about 1,00 Euro. The local dealer also has a heap of costs (transport costs of approx. 5000,- for a normal truck with 12000 kg, that is 40 cents per kilo). In addition the packing and labeling costs of approx. 10 cent come, etc.) Of course also the middleman would like to earn something locally and buys thus the commodity for 40 cent per kilo from the producer.

Thus the producer has approx. 7% of the selling price at REWE. (That’s a nice calculation, there are often enough times when the producer gets 25 cent/kg)

But we think this is normal and ok.

In network marketing the goods are recommended from person to person and the different structures deserve to have established these contacts. All costs for advertising, advertising material, websites, etc. get “stuck” with these people.

As a rule, about 5 to 10 levels are paid, in addition there are, depending on the distribution, different bonuses.

If we assume a bonus system with 10 levels from 1% to 10% are without bonuses 55%, then we are sometimes nice and add 20% more bonuses, but then the producer 25% “hangs”. Isn’t that fairer? If we assume that the producer naturally has higher costs for storage and logistics due to this system, then it is still well over 15% that remain with the producer. In this respect, the network marketing system is certainly fairer and people who work for it earn money with it.

Now the only thing that matters is that the products are in order!

Also here the viewer often loses sight of what nonsense and useless stuff he often buys in the retail trade.

Of course, there are also bad products in network marketing, but as a rule they do not stay on the market for long, because it is difficult to recommend bad products in the long run.

The bottom line for me is that network marketing with good products is fairer than retailing, that more people are rewarded for their work and not money is earned with money and it improves communication between people, because it has to be talked about and not just consumed.

These thoughts have moved us to do network marketing with Kannaway’s fantastic products, with a clear conscience and full of enthusiasm.

 

You can find high-quality products in my shop (forwarding):

The shop of Juttakann

Jutta Ferchow

Stefan Lueke

 

Tenerife takes off!

On 20.09.2018 a company presentation of Kannaway will take place. It speaks:


Beate Emmer
International Director Elite

As a special guest from the USA


Randy Schroeder
Kannaway Crown Ambassador

Kannaway is the leading supplier in full spectrum hemp oil (Without THC)
In addition to our superior products, Kannaway offers a unique partner system that enables everyone to succeed.
Our goal is to share the life-changing benefits of hemp-based cannabidiol (CBD) with every individual and family. We also want to empower everyone to do the same in their environment. Kannaway has followers around the world and a team of experienced and passionate team partners representing these products. Kannaway has earned this reputation by offering some of the highest quality CBD Hemp Oil products.

Admission is 18:00 hrs.
Start is 19:00 o’clock

You can find high-quality products in my shop (forwarding):

The shop of Juttakann

Before or after an order you are welcome to contact us, as we occasionally give away vouchers.

Kannaway’s Pure Gold is for me (after many tests of different CBD oils) the most effective CBD hemp oil product available on the Eropean market for some time!

Jutta Ferchow

Stefan Lueke